Autore
FULVIO BASOLO
Unimap Dati autore
- Professore Ordinario presso Dipartimento di Chirurgia
- Membro della Facolta' di Medicina e Chirurgia
- Settore scientifico disciplinare MED/08 ANATOMIA PATOLOGICA
- In servizio
Prodotti
- Abstract
- Advanced stage thymomas and thymic carcinomas: results of multimodality treatments 2005
- Interaction between gemcitabine and topotecan in human non-small-cell lung cancer cells: effects on cell survival, cell cycle and pharmacogenetic profile 2005
- Interleukin-8 in non-small cell lung carcinoma: relation with angiogenic pattern and p53 alterations 2005
- The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells 2005
- Type I interferons modulate the expression of thyroid peroxidase, sodium/iodide symporter, and thyroglobulin genes in primary human thyrocyte cultures. 2005
- Thymomas: clinical-pathological correlations 2006
- Tumour necrosis factor-alpha: prognostic role and relationship with interleukin-8 and endothelin-1 in non-small cell lung cancer 2006
- KRAS and BRAF mutational analyses in a phase II trial of first-line FOLFOXIRI plus bevacizumab (BV) in metastatic colorectal cancer (mCRC) patients (pts). 2009
- KRAS and BRAF mutational analyses in a phase II trial of first-line folfoxiri plus bevacizumab (BV) in metastatic colorectal cancer (MCRC) patients (pts). 2009
- Circulating amphiregulin (AR) plasma levels as surrogate pharmacodynamic markers of EGFR inhibition with cetuximab in metastatic colorectal cancer (MCRC) patients. 2010
- Articoli
- Reduced expression of interleukin 6(IL6) in undifferentiated thyroid carcinoma: in vitro in vivo studies. 1988
- Age-related activation of the thyrosine kinase receptor protooncogenes RET and NTRK1 in papillary thyroid carcinoma 1996
- Defective IL6 expression and responsiveness in human mammary cells transformed by an adeno-5/SV40 hybrid virus. 1996
- Expression of interleukin 6(IL6) and respomse to it in human mammary tumours. Cancer Res 1996
- Expression of the 67 KD laminin receptor in human thyroid cancer correlates with progression: immunohistochemical study. 1996
- Microvessel count is an indicator of poor outcome in parafollicular, but not in follicular thyroid cancer. 1996
- Neoangiogenesis: a putative marker of malignancy in non-small-cell lung cancer (NSCLC) development. 1996
- P53 and PCNA protein expression is related to the degree of differentiation in thyroid carcinomas 1996
- Angiogenesis as a prognostic indicator of survival in non-small-cell lung carcinoma: a prospective study 1997
- Apoptosis and proliferation in thyroid carcinoma: correlation with Bcl-2 and p53 protein expression. 1997
- Cytokine production by a new undifferentiated human thyroid carcinoma cell line, FB-1. 1997
- Down-regulation of the nm23.h1 gene inhibits cell proliferation. 1997
- In mammary epithelial cells p53-mediated apoptosis in response to DNA damage is dependent on the agent and can be influenced by growth factors. 1997
- Inhibition of experimental angiogenesis by the somatostatin analogue octreotide acetate (SMS 201-995). 1997
- Neoangiogenesi and p53 protein in lung cancer: their prognostic role and their relation with vascular endothelial growth factor (VEGF) expression. 1997
- c-Ha-ras transfection and expression of MDR-related genes in MCF-10A human breast cell line. 1997
- BCL2 and p53 regulate VEGF-mediated angiogenesis in non-small cell lung carcinoma. 1998
- Ectopic expression of bone sialoprotein in human thyroid cancer 1998
- Reduced expression of interleukin 6 in undifferentiated thyroid carcinoma: in vitro and in vivo studies 1998
- Simian virus 40-like DNA sequences in huma papillary thyroid carcinomas. 1998
- Espression of Interleukin 6 (IL6) correlates to estrogen receptor but not with p53 in human breast carcinomas. 1999
- Expression of Vascular Endothelial Growth Factor mRNA in Non-Small Cell Lung Carcinomas. 1999
- Genetic analysis of the TSH receptor gene in differentiated human thyroid carcinomas. 1999
- Papanicolaou-stained scrape preparations in intraoperative management of thyroid lesions. 1999
- Potentiation of the malignant phenotype of the undifferentiated ARO thyroid cell line by insertion of the BCL-2 gene. 1999
- Quantitation by competitive PCR assay of vascular endothelial growth factor (VEGF) in non-small cell lung carcinomas 1999
- TSP1 and TSP2 mRNA expression in lung carcinoma: relation with p53 alterations, angiogenic growth factors and vascular density. 1999
- Cyclin D1 Overexpression in thyroid carcinomas: Relation with clinico-pathological Parameters, retinoblastoma Gene product, and Ki67 Labeling index. 2000
- Cyclin D1 overexpression in thyroid carcinomas: relation with clinico-pathological parameters, retinoblastoma gene product, and Ki67 labeling index. 2000
- Identification of a novel subtype of H4-RET rearrangement in a thyroid papillary carcinoma and lymph node metastasis. 2000
- N-ras mutation in poorly differentiated thyroid carcinomas: correlation with bone metastases and inverse correlation to thyroglobulin expression. 2000
- New breakpoints in both the H4 and RET genes create a variant of PTC-1 in a post-Chernobyl papillary thyroid carcinoma. 2000
- RET rearrangements in papillary thyroid carcinomas and adenomas detected by interphase FISH. 2000
- Suppression of Fas expression and down-regulation of Fas ligand in highly aggressive human thyroid carcinoma. 2000
- Surgical and pathological changes after percutaneous ethanol injection therapy of thyroid nodules 2000
- Tumour necrosis factor-alpha and transforming growth factor-beta are significantly associated with better prognosis in non-small cell lung carcinoma: putative relation with BCL-2-mediated neovascularization. 2000
- Alterations of Fas (APO1-CD95) gene and its relationship with p53 in non-small cell lung cancer 2001
- Contralateral papillary thyroid cancer is frequent at completion thyroidectomy with no difference in low- and high-risk patients. 2001
- RET/PTC rearrangements in thyroid nodules: studies in irradiated and not irradiated, malignant and benign thyroid lesions in children and adults. 2001
- The multimodality treatment of thymic carcinoma. 2001
- Thymic carcinoma: a report of 13 cases. 2001
- A high vascular count and overexpression of vascular endothelial growth factor are associated with unfavourable prognosis in operated small cell lung carcinoma. 2002
- BOGAZZI F, AGHINI-LOMBARDI F, COSCI C, LUPI I, SANTINI F., TANDA ML, MICCOLI P, BASOLO F, PINCHERA A, BARTALENA L, BRAVERMAN LE, MARTINO E. Iopanoic acid rapidly controls Type I amiodarone-induced thyrotoxicosis prior to thyroidectomy. 2002
- Cytotoxic effects of carboplatinum and epirubicin in the setting of an elevated serum thyrotropin for advanced poorly differentiated thyroid cancer. 2002
- DNA Immunization of Mice against the VP1 Capsid Protein of Coxsackievirus B4. 2002
- Establishment of a non-tumorigenic papillary thyroid cell line (FB-2) carrying the RET/PTC1 rearrangement. 2002
- Evaluation of telomerase in the development and progression of colon cancer. 2002
- Evaluation of telomerase mRNA (hTERT) in colon cancer. 2002
- Identification of Fas (APO-1/CD95) and p53 gene mutations in non-small cell lung cancer. 2002
- Lopanoic acid rapidly controls type I amiodarone-induced thyrotoxicosis prior to thyroidectomy. 2002
- Potent mitogenicity of the RET/PTC3 oncogene correlates with its prevalence in tall-cell variant of papillary thyroid carcinoma. 2002
- SANTINI F., BOTTICI V, ELISEI R, MONTANELLI L, MAZZEO S, BASOLO F, PINCHERA A, PACINI F Cytotoxic effects of carboplatinum and epirubicin in the setting of an elevated serum thyrotropin for advanced poorly differentiated thyroid cancer. 2002
- BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas. 2003
- Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2). 2003
- Evaluation of telomerase in non-melanoma skin cancer. 2003
- Galectin-3 and oncofetal-fibronectin expression in thyroid neoplasia as assessed by reverse transcription-polymerase chain reaction and immunochemistry in cytologic and pathologic specimens. 2003
- Prevalence of cancer in follicular thyroid nodules: is there still a role for intraoperative frozen section analysis? 2003
- Simian virus 40-like sequences from early and late regions in human thyroid tumors of different histotypes. 2003
- Telomerase in intracranial meningiomas. 2003
- Analysis of BRAF point mutation and RET/PTC rearrangement refines the fine-needle aspiration diagnosis of papillary thyroid carcinoma 2004
- Autocrine stimulation by osteopontin plays a pivotal role in the expression of the mitogenic and invasive phenotype of RET/PTC-transformed thyroid cells. 2004
- Biscolla RP, Ugolini C, Sculli M, Bottici V, Castagna MG, Romei C, Cosci B, Molinaro E, Faviana P, Basolo F, Miccoli P, Pacini F, Pinchera A, Elisei R.: Medullary and papillary tumors are frequently associated in the same thyroid gland without evidence of reciprocal influence in their biologic behavior. 2004
- Description of a novel germline RET mutation (Ala883Thr) in exon 15 able to determine the Medullary thyroid carcinoma phenotype only in homozygous condition 2004
- Elisei R, Cosci B, Romei C, Agate L, Piampiani P, Miccoli P, Berti P, Basolo F, Ugolini C, Ciampi R, Nikiforov Y, Pinchera A.: Identification of a novel point mutation in the RET gene (Ala883Thr), which is associated with medullary thyroid carcinoma phenotype only in homozygous condition. 2004
- Functional expression of the CXCR4 chemokine receptor is induced by RET/PTC oncogenes and is a common event in human papillary thyroid carcinomas. 2004
- Impact of routine measurement of serum calcitonin on the diagnosis and outcome of medullary thyroid cancer: experience in 10,864 patients with nodular thyroid disorders. 2004
- Impact of routine measurement of serum calcitonin on the diagnosis and outcome of medullary thyroid cancer: experience in 10,864 patients with nodular thyroid disorders. 2004
- Plasma and tissue chromogranin in patients with adrenocortical adenomas. 2004
- Plasma chromogranin A in incidental non-functioning, benign, solid adrenocortical tumors. 2004
- Regulation of telomerase and its hTERT messenger in colorectal cancer. 2004
- Thyroid papillary carcinoma: preliminary evidence for a germ-line single nucleotide polymorphism in the Fas gene. 2004
- All-trans retinoic acid treatment inhibits the growth of RAR mRNA expressing thyroid cancer cell lines but does not re-induce the expression of thyroid specific genes 2005
- Elisei R, Vivaldi A, Agate L, Ciampi R, Molinaro E, Piampiani P, Romei C, Faviana P, Basolo F, Miccoli P, Capodanno A, Collecchi P, Pacini F, Pinchera A. : All-trans-retinoic acid treatment inhibits the growth of retinoic acid receptor beta messenger ribonucleic acid expressing thyroid cancer cell lines but does not reinduce the expression of thyroid-specific genes. 2005
- Expression of endothelin-1 is related to poor prognosis in non-small cell lung carcinoma. 2005
- Mitogenic effects of the up-regulation of minichromosome maintenance proteins in anaplastic thyroid carcinoma. 2005
- Osteopontin expression and prognostic significance in non-small cell lung cancer. 2005
- Osteopontin is overexpressed in human papillary thyroid carcinomas and enhances thyroid carcinoma cell invasiveness. 2005
- Prognostic significance of osteopontin expression in early-stage non-small-cell lung cancer. 2005
- Proliferative activity of extracellular HIV-1 Tat protein in human epithelial cells: expression profile of pathogenetically relevant genes 2005
- Expression of endothelin 1 and its angiogenic role in meningiomas. 2006
- Incidental thyroid carcinoma in a large series of consecutive patients operated on for benign thyroid disease 2006
- Neoadjuvant chemotherapy for stage III and IVA thymomas: a single-institution experience with a long follow-up. 2006
- TELOMERASE ACTIVITY IN hTERT mRNA EXPRESSION IN GLIAL TUMORS 2006
- Treatment with drugs able to reduce iodine efflux significantly increases the intracellular retention time in thyroid cancer cells stably transfected with sodium iodide symporter complementary deoxyribonucleic acid 2006
- A cell proliferation and chromosomal instability signature in anaplastic thyroid carcinoma 2007
- Association of BRAF V600E mutation with poor clinicopathological outcomes in 500 consecutive cases of papillary thyroid carcinoma. 2007
- Biological role and potential therapeutic targeting of the chemokine receptor CXCR4 in undifferentiated thyroid cancer 2007
- Clinical features of thyroid autoimmunity are associated with thyroiditis on histology and are not predictive of malignancy in 570 patients with indeterminate nodules on cytology who had thyroidectomy 2007
- Clinically unpredictable prognostic factors in the outcome of medullary thyroid cancer. 2007
- Combined clinical, thyroid ultrasound and cytological features help to predict thyroid malignancy in follicular and Hupsilonrthle cell thyroid lesions: results from a series of 505 consecutive patients. 2007
- Galectin-3 is highly expressed in nonencapsulated papillary thyroid carcinoma but weakly expressed in encapsulated type; comparison with Hector Battifora mesothelial cell 1 immunoreactivity. 2007
- Intrathyroidal differentiated thyroid carcinoma: tumor size-based surgical concepts 2007
- Lymphocyte and immature dendritic cell infiltrates in differentiated, poorly differentiated, and undifferentiated thyroid carcinoma. 2007
- Presence of BRAF V600E in very early stages of papillary thyroid carcinoma. 2007
- Proteomic analysis of human thyroid fine needle aspiration fluid 2007
- RET genetic screening in patients with medullary thyroid cancer and their relatives: experience with 807 individuals at one center. 2007
- Role of frozen section associated with intraoperative cytology in comparison to FNA and FS alone in the management of thyroid nodules 2007
- The heterogeneous distribution of BRAF mutation supports the independent clonal origin of distinct tumor foci in multifocal papillary thyroid carcinoma 2007
- WWOX expression in different histologic types and subtypes of non-small cell lung cancer. 2007
- BRAF(V600E) mutation and outcome of patients with papillary thyroid carcinoma: a 15-year median follow-up study. 2008
- BRAFV600E mutation, but not RET/PTC rearrangements, is correlated with a lower expression of both thyroperoxidase and sodium iodide symporter genes in papillary thyroid cancer 2008
- Characterization of thyroglobulin epitopes in patients with autoimmune and non-autoimmune thyroid diseases using recombinant human monoclonal thyroglobulin autoantibodies. 2008
- Evaluation of the sensitivity to chemotherapeutics or thiazolidinediones of primary anaplastic thyroid cancer cells obtained by fine-needle aspiration. 2008
- Fine-Needle Aspiration of Thyroid Nodules: Proteomic Analysis To Identify Cancer Biomarkers. 2008
- Functional characterization of the novel T599I-VKSRdel BRAF mutation in a follicular variant papillary thyroid carcinoma. 2008
- Galectin-3-expression analysis in the surgical selection of follicular thyroid nodules with indeterminate fine-needle aspiration cytology: a prospective multicentre study 2008
- Papillary thyroid cancer: pathological parameters as prognostic factors in different classes of age. 2008
- Prognostic significance of somatic RET oncogene mutations in sporadic medullary thyroid cancer: a 10-year follow-up study. 2008
- Surgical treatment of pleural recurrence from thymoma. 2008
- A ganglioneuroma with features of a thyroid nodule: intense pain on fine needle biopsy as a diagnostic clue. 2009
- Association of thymoma and myasthenia gravis: oncological and neurological results of the surgical treatment. 2009
- Dysregulation of secretion of CXC alpha-chemokine CXCL10 in papillary thyroid cancer: modulation by peroxisome proliferator-activated receptor-gamma agonists. 2009
- KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer. 2009
- Lower levels of TSH are associated to a lower risk of papillary thyroid cancer in patients with thyroid nodular disease: thyroid autonomy may play a protective role. 2009
- Management of pleural recurrence after curative resection of thymoma. 2009
- Thiazolidinediones and antiblastics in primary human anaplastic thyroid cancer cells. 2009
- Are the clinical and pathological features of differentiated thyroid carcinoma really changed over the last 35 years? Study on 4187 patients from a single Italian institution to answer this question. 2010
- BRAF status of follicular variant of papillary thyroid carcinoma and its relationship to its clinical and cytological features. 2010
- CXC chemokine receptor 4 immunodetection in the follicular variant of papillary thyroid carcinoma: comparison to galectin-3 and hector battifora mesothelial cell-1. 2010
- Correlation between the BRAF V600E Mutation and Tumor Invasiveness in Papillary Thyroid Carcinomas Smaller than 20 Millimeters: Analysis of 1060 Cases. 2010
- Extracellular superoxide dismutase is a thyroid differentiation marker downregulated in cancer. 2010
- L-thyroxine-treated patients with nodular goiter have lower serum TSH and lower frequency of papillary thyroid cancer: results of a cross-sectional study on 27 914 patients. 2010
- Male sex, single nodularity, and young age are associated with the risk of finding a papillary thyroid cancer on fine-needle aspiration cytology in a large series of patients with nodular thyroid disease. 2010
- Real-time elastosonography: useful tool for refining the presurgical diagnosis in thyroid nodules with indeterminate or nondiagnostic cytology. 2010
- A proteomic approach to study parathyroid glands 2011
- CXCR4 expression correlates with the degree of tumor infiltration and BRAF status in papillary thyroid carcinomas 2011
- Chromosome 10 and RET gene copy number alterations in hereditary and sporadic Medullary Thyroid Carcinoma. 2011
- Effects of esomeprazole on healing of non-steroidal anti-inflammatory drug (NSAID)-induced gastric ulcers in the presence of a continued NSAID treatment: characterization of molecular mechanisms 2011
- Evaluation of formalin-fixed paraffin-embedded tissues in the proteomic analysis of parathyroid glands. 2011
- Hashimoto's thyroiditis is associated with papillary thyroid carcinoma: role of TSH and of treatment with L-thyroxine 2011
- Is Elastography Actually Useful in the Presurgical Selection of Thyroid Nodules with Indeterminate Cytology? 2011
- RET genetic screening of sporadic medullary thyroid cancer (MTC) allows the preclinical diagnosis of unsuspected gene carriers and the identification of a relevant percentage of hidden familial MTC (FMTC). 2011
- Somatostatin analogues do not affect calcium metabolism in patients with acromegaly and primary hyperparathyroidism corrected due to MEN 1-like syndrome. 2011
- Atti, Riassunti o Comunicazioni
- Small papillary thyroid carcinoma: good biological behaviour of intrathyroidal mPTC 2005
- BRAFV600E mutation in a series of incidental papillary thyroid carcinomas 2006
- CLINICAL APPLICATION OF MOLECULAR BIOLOGY ANALYSIS IN FINE NEEDLE ASPIRATION (FNA) OF THYROID NODULES 2006
- Familial medullary thyroid carcinoma (FMTC) prevalence in a serie of 773 subjects screened for RET gene mutations 2006
- High prevalence of familial medullary thyroid carcinoma (FMTC) in apparently sporadic MTC harbouring a RET germline mutation 2006
- Molecular analysis of BRAF mutation, RETPTC and TRK rearrangements in fine needle aspiration (FNA)of thyroid nodules with non nondiagnostic cytology 2006
- New features of differentiated thyroid carcinoma diagnosed in the last 15 years 2006
- PREVALENZA DI BRAFV600E E RETPTC NEL CARCINOMA PAPILLARE DELLA TIROIDE E LORO CORREALAZIONE CON L’ ESPRESSIONE DEI GENI DI DIFFERENZIAZIONE TIROIDEA. 2006
- Potential use of tissue and blood oncofibronectin mRNA for the diagnosis of primary and metastatic differentiated thyroid cancer 2006
- Usefulness of molecular analysis of BRAF mutation and RETPTC rearrangements in fine needle aspiration (FNA) of thyroid noduleswith non diagnostic cytology 2006
- Utilizzo del profilo di espressione genica per la diagnosi di patologie maligne tiroidee 2006
- braf mutation in a selected series of multifocal and metastatic papillary thyroid carcinomas 2006
- differentiated thyroid carcinoma: are clinical and pathological features changing? 2006
- presence of neoplastic capsule is an indicator of good prognosis in papillary thyroid carcinoma 2006
- tissue and blood oncofibronectin mRNA as marker of primary and metastatic papillary thyroid cancer 2006
- BRAFV600E mutations are correlated with a lower expression of both NIS and TPO mRNA expression in papillary thyroid cancer (PTC) 2007
- Expression gene profile may be useful for the diagnosis of thyroid malignancies. 2007
- Il riarrangiamento Akap9-Braf non č presente nei bambini con carcinoma papillare sporadico della tiroide. 2007
- TELOMERASE ACTIVITY AND H-TERT MRNA EXPRESSION IN GLIOMAS 2007
- ANALYSIS OF ALTERNATIVE MECHANISMS OF RET GENE ACTIVATION IN FAMILIAL AND SPORADIC MEDULLARY THYROID CARCINOMA 2009
- ANALYSIS OF RET GENE AND CHROMOSOME 10 COPY NUMBER VARIATION IN FAMILIAL AND SPORADIC MEDULLARY THYROID CARCINOMA 2009
- RAS-ERK SIGNALLING PATHWAY IS ACTIVATED BOTH IN RET MUTATED AND NON MUTATED MEDULLARY THYROID CARCINOMAS 2009
- RET GENE ACTIVATION IN MEDULLARY THYROID CARCINOMA: ANALYSIS OF ALTERNATIVE MECHANISMS 2009
- Effects of proton pump inhibitors on healing of NSAID-induced gastric ulcerations in the presence of a continued NSAID treatment: characterization of molecular mechanisms. 2010
- Il ricorso ad una meta-analisi per studiare l’associazione tra la mutazione del gene BRAF e la presenza di metastasi linfonodali da carcinoma papillare tiroideo. 2010
- COLON CANCER DIAGNOSIS: A PROTEOMIC APPROACH TO SEARCH POTENTIAL BIOMARKERS 2011
- Capitoli, Parte,Saggi, Studi, Articoli in libro