Autore
SIMONA DANIELE
Dati autore
- Dottorando presso Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie
- Dottorato di Scienza del Farmaco e delle Sostanze Bioattive
- Non più in servizio
Prodotti
- Articoli
- Functional characterization of two isoforms of the P2Y-like receptor GPR17: 35SGTPgammaS binding and electrophysiological studies in 1321N1 cells. 2009
- Adenosine receptors: what we know and what we are learning. 2010
- Frontal affinity chromatography-mass spectrometry useful for characterization of new ligands for GPR17 receptor. 2010
- New fluoro derivatives of the pyrazolo5,1-c1,2,4benzotriazine 5-oxide system: evaluation of fluorine binding properties in the benzodiazepine site on γ-aminobutyrric acid type A (GABAA) receptor. Design, synthesis, biological and molecular modeling investigation. 2010
- Novel N2-substituted pyrazolo3,4-dpyrimidine adenosine A3 receptor antagonists: inhibition of A3-mediated human glioblastoma cell proliferation. 2010
- Receptor cross-talk: haloperidol treatment enhances A2A adenosine receptor functioning in a transfected cell model. 2010
- Regulation of PC12 cell survival and differentiation by the new P2Y-like receptor GPR17. 2010
- A2A adenosine receptor binding parameters in platelets from patients affected by pathological gambling 2011
- Agonist-Induced Desensitization/Resensitization of Human G Protein-Coupled Receptor 17: A Functional Cross-Talk between Purinergic and Cysteinyl-Leukotriene Ligands 2011
- Derivatives of Benzimidazol-2-ylquinoline and Benzimidazol-2-ylisoquinoline as Selective A(1) Adenosine Receptor Antagonists with Stimulant Activity on Human Colon Motility. 2011
- Development of ligands at γ-aminobutyrric acid type A (GABA(A)) receptor subtype as new agents for pain relief 2011
- In silico identification of new ligands for GPR17: a promising therapeutic target for neurodegenerative diseases. 2011
- New 3-, 8-disubstituted pyrazolo5,1-c1,2,4benzotriazines useful for studying the interaction with the HBp-3 area (hydrogen bond point area) in the benzodiazepine site on the γ-aminobutyric acid type A (GABAA) receptor. 2011
- New Insight into the Central Benzodiazepine Receptor–Ligand Interactions: Design, Synthesis, Biological Evaluation, and Molecular Modeling of 3-Substituted 6-Phenyl-4H-imidazo1,5-a1,4benzodiazepines and Related Compounds 2011
- PHENOTYPIC CHANGES, SIGNALING PATHWAY AND FUNCTIONAL CORRELATES OF GPR17-EXPRESSING NEURAL PRECURSOR CELLS DURING OLIGODENDROCYTE DIFFERENTIATION 2011
- Substituted pyrazolo3,4-bpyridines as human A(1) adenosine antagonists: Developments in understanding the receptor stereoselectivity. 2011
- The Identification of the 2-Phenylphthalazin-1(2H)-one Scaffold as a New Decorable Core Skeleton for the Design of Potent and Selective Human A(3) Adenosine Receptor Antagonists. J Med Chem. 2011
- Atti, Riassunti o Comunicazioni
- EXPRESSION AND ACTIVITY OF GPR17, A NEW NUCLEOTIDE-CYSTEINYL-LEUKOTRIENE RECEPTOR, IN NEURONAL PC12 CELL MODEL. 2008
- Translocator Protein (TSPO) and identification of new molecular diagnosis tools 2008
- Effect of typical and atypical antipsychotics on A2A adenosine receptor affinity and functional parameters in CHO transfected cells 2009
- Functional cross-talk between GPR17 and nerve growth factor in neuronal pheocromocytoma PC12 cell proliferation and differentiation. 2009
- Purinergic signaling and cell proliferation and differentiation in a neuronal pheocromocytoma PC12 cell model 2009
- Pyrazolo1’,5’:1,6pyrimido4,5-dpyridazin-4(3H)-one as ligands of adenosine receptors 2009
- Rational Design and Synthesis of Potent and Selective Adenosine Receptor Antagonists 2009
- Synthesis and biological evaluation on human glioblastoma cells of novel pyrazolo3,4-Dpyrimidine adenosine A3 receptor antagonists. 2009
- A new small molecule, D2 dopamine receptor agonist, as an allosteric modulator of A2A adenosine receptor signalling 2010
- A new small molecule, D2 dopamine receptor agonist, as an allosteric modulator of A2A adenosine receptor signalling 2010
- A new small molecule, D2 dopamine receptor agonist, as an allosteric modulator of A2A adenosine receptor signalling 2010
- EPOalfa and DarbEPO-mediated erythropoietin receptor desensitization/resensitization 2010
- Frontal Affinity Chromatography-Mass Spectrometry Useful for Characterization of New Ligands for GPR17 Receptor 2010
- GPR17 desensitization: cross-regulation between the purinergic and leukotriene binding site. 2010
- Studio clinico e neurobiologico in pazienti affetti da gioco d’azzardo patologico 2010
- Studio sui trasportatori di GABA e glutammato nelle piastrine di soggetti con disturbo bipolare 2010
- The P2Y-like GPR17 receptor orchestrates the transition between immature and myelinating oligodendrocytes and is a new target for myelin repair 2010
- 3-Aryl-1,2,4triazino4,3-abenzimidazol-4(10H)-one: a novel template for the design of highly selective A2B adenosine receptor antagonists. 2011
- Adenosine A2A receptors and psychiatric disorders 2011
- Agonist-induced desensitisation/resensitisation of human GPR17: a functional cross-talk between purinergic and cysteinyl-leukotriene ligands 2011
- D2 dopamine receptor agonists as allosteric modulators of A2A adenosine receptor signalling 2011
- GPR17 ligands: synthesis and characterization of new potent agonists. 2011
- Receptor insight: recent advances in the development of novel therapeutic agents 2011
- Role of the P2Y-like receptor GPR17 in neural precursor cells 2011